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Efficient biocatalyst for large-scale synthesis of cephalosporins, obtained by combining immobilization and site-directed mutagenesis of penicillin acylase

Cecchini, Davide ; Pavesi, Roberto ; Sanna, Sara ; Daly, Simona ; Xaiz, Roberto ; Pregnolato, Massimo ; Terreni, Marco

Applied Microbiology and Biotechnology, 2012, Vol.95(6), pp.1491-1500 [Rivista Peer Reviewed]

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Improved activity and pH stability of E. coli ATCC 11105 penicillin acylase by error-prone PCR

Balci, Huseyin ; Ozturk, Merve ; Pijning, Tjaard ; Ozturk, Saliha ; Gumusel, Fusun

Applied Microbiology and Biotechnology, 2014, Vol.98(10), pp.4467-4477 [Rivista Peer Reviewed]

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One-pot, two-step enzymatic synthesis of amoxicillin by complexing with Zn 2+

Zhang, Ye-Wang ; Liu, Rui-Jiang ; Xu, Xi-Ming

Applied Microbiology and Biotechnology, 2010, Vol.88(1), pp.49-55 [Rivista Peer Reviewed]

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A green and expedient synthesis of enantiopure diketopiperazines via enzymatic resolution of unnatural amino acids

Pereira, Pedro C ; Arends, Isabel W.C.E ; Sheldon, Roger A

Tetrahedron Letters, 03 September 2014, Vol.55(36), pp.4991-4993 [Rivista Peer Reviewed]

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The βD484N mutant of penicillin acylase from Escherichia coli is more resistant to inactivation by substrates and can effectively perform peptide synthesis in aqueous medium

Shcherbakova, Tatyana A ; Panin, Nikolay V ; Suplatov, Dmitry A ; Shapovalova, Irina V ; Švedas, Vytas K

Journal of Molecular Catalysis. B, Enzymatic, February 2015, Vol.112, pp.66-68 [Rivista Peer Reviewed]

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Immobilization of Penicillin Acylase on Macroporous Adsorption Resin CLX1180 Carrier

Liu, Donglei ; Chen, Zhenbin ; Long, Jiapeng ; Zhao, Yingyu ; Du, Xueyan

Advances in Polymer Technology, April 2018, Vol.37(3), pp.753-760 [Rivista Peer Reviewed]

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Evaluation of kinetic parameters of immobilized penicillin G acylase subject to an inactivation and reactivation process

Romero, Oscar ; Araya, Erick ; Illanes, Andrés ; Wilson, Lorena

Journal of Molecular Catalysis. B, Enzymatic, June 2014, Vol.104, pp.70-74 [Rivista Peer Reviewed]

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Comparative study of the enzymatic synthesis of cephalexin at high substrate concentration in aqueous and organic media using statistical model

Bahamondes, Carola ; Wilson, Lorena ; Aguirre, Carolina ; Illanes, Andrés

Biotechnology and Bioprocess Engineering, 2012, Vol.17(4), pp.711-721 [Rivista Peer Reviewed]

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Supermacroporous hydrophobic affinity sorbents for penicillin acylase purification

Demirçelik, Ahmet Hamdi ; Perçin, Işık ; Denizli, Adil

Journal of Macromolecular Science, Part A, 01 February 2017, Vol.54(2), pp.71-79 [Rivista Peer Reviewed]

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Effect of Internal Diffusional Restrictions on the Hydrolysis of Penicillin G: Reactor Performance and Specific Productivity of 6-APA with Immobilized Penicillin Acylase

Valencia, Pedro ; Flores, Sebastián ; Wilson, Lorena ; Illanes, Andrés

Applied Biochemistry and Biotechnology, 2011, Vol.165(2), pp.426-441 [Rivista Peer Reviewed]

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da questo autore/creatore:

  1. Illanes, A
  2. Fernandez-Lafuente, R
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