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Molecular hematology

Drew Provan 1955-; John Gribben

Chichester, West Sussex ; Hoboken, NJ : Wiley-Blackwell ; 2010

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  • Titolo:
    Molecular hematology
  • Altro autore: Drew Provan 1955-; John Gribben
  • Editore: Chichester, West Sussex ; Hoboken, NJ : Wiley-Blackwell
  • Anno: 2010
  • Descrizione fisica: 1 online resource (450 p.).
  • Descrizione: Molecular Hematology; Contents; Contributors; Foreword; Preface to the third edition; Abbreviations; Chapter 1: Beginnings: the molecular pathology of hemoglobin; Chapter 2: Molecular cytogenetics and array-based genomic analysis; Chapter 3: Stem cells; Chapter 4: The genetics of acute myeloid leukemias; Chapter 5: Secondary myelodysplasia/acute myelogenous leukemia: assessment of risk; Chapter 6: Detection of minimal residual disease in hematological malignancies; Chapter 7: Chronic myelogenous leukemia; Chapter 8: Myelodysplastic syndromes; Chapter 9: Myeloproliferative disorders
    Chapter 10: Lymphoma geneticsChapter 11: The molecular biology of multiple myeloma; Chapter 12: The molecular basis of anemia; Chapter 13: Anemia of chronic disease; Chapter 14: The molecular basis of iron metabolism; color plates: 1-10; Chapter 15: Hemoglobinopathies due to structural mutations; Chapter 16: Molecular pathogenesis of malaria; Chapter 17: Molecular coagulation and thrombophilia; Chapter 18: The molecular basis of hemophilia; Chapter 19: The molecular basis of von Willebrand disease; Chapter 20: Platelet disorders; Chapter 21: The molecular basis of blood cell alloantigens
    Chapter 22: Functions of blood group antigensChapter 23: Autoimmune hematological disorders; color plates: 11-22; Chapter 24: Hematopoietic growth factors: a 40-year journey from crude "activities" to therapeutic proteins; Chapter 25: Molecular therapeutics in hematology: gene therapy; Chapter 26: Pharmacogenomics; Chapter 27: Gene expression profiling in the study of lymphoid malignancies; Chapter 28: History and development of molecular biology; Chapter 29: Cancer stem cells; Chapter 30: Molecular basis of transplantation; Appendix 1: Glossary; Appendix 2: Cytogenetic glossary
    Appendix 3: Cluster designation (CD) antigens used in this bookIndex
    Now in its third edition, Molecular Hematology has been thoroughly updated to incorporate recent advances in molecular research. The aim of the book remains the same - to provide a core knowledge base for those with little exposure to molecular biological techniques. Molecular biology has had a significant impact on the understanding of blood diseases and this book shows how molecular techniques can be used in diagnosis and treatment. In each chapter the authors summarize the impact made by molecular research on the understanding of the pathogenesis of the disorder featured, and highl
  • Soggetti: Blood -- Diseases -- Molecular aspects; Internal medicine; Electronic books
  • Lingua: Inglese
  • Identificativo: ISBN: 1-282-48241-6;ISBN: 9786612482410;ISBN: 1-4443-1853-5;ISBN: 1-4443-1854-3
  • Lo trovi in: Risorse Elettroniche UniNA "Federico II"

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